Although the therapeutic effect of hydrogen on diseases has been recognized for a short time, the biological safety of hydrogen has long been widely studied. Decades ago, diving medical research proved that breathing high-pressure hydrogen for several days would not cause any toxic damage to divers. Up to now, almost all the research topics of hydrogen-oxygen diving involve the safety of hydrogen gas. In particular, Sweden and France have successfully conducted a series of human hydrogen-oxygen diving experiments. For example, during 1988-1989, the time of human diving in France was as long as 7,200 hours, which further demonstrated that human breathing hydrogen and hydrogen-oxygen diving are safe. Since hydrogen is not toxic when breathed at high pressure, it is safer to ingest hydrogen at normal pressure.
As research on hydrogen biology continues to grow, so do clinical studies on hydrogen. So far, there is no evidence that hydrogen is harmful to humans. Data on hydrogen biosafety published by the European Union and the United States governments show that hydrogen does not have any acute or chronic toxicity to humans at atmospheric pressure. The National Health Commission issued the national standard for hydrogen as a food additive in December 2014, GB31633-2014 National Standard for Food Safety Hydrogen as a Food Additive.
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